[SECAL-L ] Fwd: News from the Center for Alternatives to Animal Testing (CAAT)

De: comunicacion@secal.es
Mon, 27 Jul 2020 20:55:46 +0200
——————————-
Buenas noches,
Os enviamos las noticias semanales de CCAT.
Saludos

Carlos Carnero / Garikoitz Azkona
Vocalia de Comunicacion Secal
comunicacion@secal.es

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Begin forwarded message:

> From: «Center for Alternatives to Animal Testing (CAAT)»
> Date: 27 July 2020 at 19:29:58 CEST
> To: Isabel
> Subject: News from the Center for Alternatives to Animal Testing (CAAT)
> Reply-To:
>
> 
> Updates from the Center for Alternatives to Animal Testing (CAAT)
> Email not displaying correctly?
> View it in your browser.
>
> CAATwalk
> July 27, 2020
> News and Updates from CAAT
> Contents:
> CAAT’s Fast-Track Grants for Non-Animal Approaches to COVID-19 Research: Grantees Announced
> Humane Society International and Humane Society of the U.S. Support CAAT’s COVID-19 Grants
> Thomas Hartung Interview on NBCLX News (Video)
> Thomas Hartung on the Discovery of Active Properties of «Inactive» Drug Ingredients (The Scientist)
> Thomas Hartung on «COVID-19: What is in the Box of Alternative Methods?»
> Jamie DeRita Memorial Animal Protection Symposium (Watch Now)
> Next Generation Humane Science Award: DEADLINE AUGUST 1, 2020
> CAAT Faculty Receive Excellent Ratings
> LIVe2021: Lung In Vitro Event for Innovative & Predictive Models
>
>
>
> CAAT’s Fast-Track Grants for Non-Animal Approaches to COVID-19 Research: Grantees Announced
> In response to the global COVID-19 pandemic, the Johns Hopkins Center for Alternatives to Animal Testing (CAAT) at the Bloomberg School of Public Health redirected a portion of the Alan and Helene Goldberg In Vitro Toxicology Grants to development of tools to address the emerging health threats. This new initiative is our Fast-track grant for research on non-animal approaches to investigate mechanisms, medicines, and vaccines for coronaviruses.
>
> You can find further details about the grant awardees here.
>
> We would like to thank Animalfree Research, Humane Society International, and Humane Society of the United States for their generous financial support of these grants.
>
> CAAT received 60+ applications, and all were of high quality, making the decision difficult. We would like to thank all of those who applied, and—if further funding should become available—may consider awarding additional applicants. The awardees and finalists are listed below.
>
> Awardees
>
> Christine Bear
> Senior Scientist, Programme in Molecular Medicine
> Hospital for Sick Children
> Development of a platform for SARS-CoV-2 therapy testing and development using primary nasal epithelial cultures
>
> Parastoo Khoshakhlagh
> Co-founder, President and CEO
> GC Therapeutics, Inc.
> Investigating the effects of hypertension drugs on the Infectivity of SARS-CoV-2 in synthetically accelerated vascularized type II pneumocyte-containing pulmonary organoids
>
> Finalists
>
> Nina Bhardwaj
> Icahn School of Medicine at Mount SinaI
>
> Joaquin Dopazo
> Fundacion Progreso y Salud
>
> Yotam Drier
> Hebrew University of Jerusalem
>
> Stagljar Igor
> Mediterranean Institute for Life Sciences
>
> Sergei V. Kotenko
> Rutgers, The State University of New Jersey
>
> Maike Windbergs
> Goethe University Frankfurt
> More information about the grants and the awardees, including abstracts, may be found here.
>
>
>
> Humane Society International and Humane Society of the U.S. Support CAAT’s COVID-19 Grants
> Humane Society International and the Humane Society of United States have supported CAAT’s fast-track research grant for non-animal approaches to investigate mechanisms, medicines, and vaccines for the novel coronavirus and COVID-19. The organizations believe that understanding the biological mechanisms that make humans especially susceptible to COVID-19 is urgently needed to inform the development and evaluation of effective countermeasures.
>
> Laboratory investigations of human disease often attempt to artificially reproduce a condition in animals. Since the World Health Organization declared COVID-19 a pandemic, a flood of studies have described infecting mice, hamsters, ferrets, monkeys and other animals with COVID-19. Yet most report that the animals used were either immune to the new virus, or manifested symptoms that differ substantially from the human condition, including in the most severe clinical outcomes. In addition, the animal-based approach is limited in its ability to predict the impact of comorbidities—the presence of two chronic diseases—in COVID-19 patients, or how the various treatments could impact or worsen the infection.
>
> “We have great faith in the Johns Hopkins Center for Alternatives to Animal Testing as a source of funding for research with the potential to spare humans, as well as animals in laboratories, from suffering caused by COVID-19,” says Kitty Block, president and CEO of HSUS and CEO of HSI.
>
> The two organizations’ donation of $20,000 to the CAAT grant program aims to stimulate innovative and inherently human-relevant solutions for COVID-19. Models based on human biology—from cell and tissue cultures to complex organoids, organs-on-a-chip, and computational tools—can help scientists understand the mechanisms of disease progression and rapidly identify interventions that are effective and safe in a human biological environment.
>
> The groups previously released a multi-pronged policy plan for preventing another global health crisis like COVID-19.
>
> Full Press Release from HSI
>
>
>
>
> Thomas Hartung Interview on NBCLX News (Video)
> How “Mini-Brains” Grown in the Lab Are Helping Researchers Study the Coronavirus
>
> “Mini-brains” are minuscule organoids made from stem cells that mimic the behavior of the human brain. A team at Johns Hopkins University is using “mini-brains” to study the affects of the coronavirus on the brain without using animal research. Thomas Hartung joined LX News to talk about what his team is learning from this research.
>
> Watch Now (NBC LX News)
>
>
>
> Thomas Hartung on the Discovery of Active Properties of «Inactive» Drug Ingredients (The Scientist)
> Excerpt:
>
> The success of a drug often depends not simply on the active ingredients it contains, but on how it is formulated, explains Thomas Hartung, a pharmacologist at Johns Hopkins University who also did not participate in the research. The inactive components may stabilize the drug, prevent contamination, control the drug’s metabolism, or improve its taste or identification. But, Hartung continues, there is a sort of “toxicological ignorance” about these substances in part because they are largely considered safe and because to screen them is an “enormous burden” and costly.
>
> The new study, which was an academia-industry collaboration funded in part by the US Food and Drug Administration (FDA), has made great inroads to addressing this “silent area,” Hartung says, and has shown “that among very many innocent substances there can be a black sheep” that we should “have an eye on.”
>
> Activities Discovered for Some Inactive Drug Ingredients (The Scientist)
>
>
>
>
> Thomas Hartung on «COVID-19: What is in the Box of Alternative Methods?»
> August 26, 2020
> Online
>
>
> The 11th World Congress on Alternatives and Animal Use in the Life Science will organize two 1.5 hour webinars on the 3Rs in COVID-19 research. On both days, several presentations will highlight innovative model systems to study COVID-19, and will also discuss new strategies for the development of vaccines, therapeutics, and diagnostics.
>
> Thomas Hartung will be speak on «COVID-19—What is in the Box of Alternative Methods?» on Wednesday, August 26th.
>
> Register now (free)
>
>
>
> Jamie DeRita Memorial Animal Protection Symposium (Watch Now)
> The Jamie Derita Memorial Animal Protection Symposium was held online (via Zoom) on July 9th, 2020. This symposium honored the life of Jamie DeRita, who passed away in June 2020.
>
> Jamie was CAAT’s event coordinator from 2012-2018, and was known to many of our friends and colleagues for her tireless work on our many meetings, conferences and symposia over the years.
>
> Jamie was famous throughout the Maryland shelter and animal welfare communities as someone who could not say no to helping any animal that needed a home. She was known to regularly pick up animals she saw in her daily travels, and to work non-stop to find them perfect homes. Her CAAT family will honor her with a series of presentations about our deep relationship with animals and adoption of lab animals, with brief testimonials from family and friends interspersed throughout the event.
>
> Guest Speakers included Aysha Akhtar (Our Shared Destiny with Animals), Stacy M. Lopresti-Goodman (From «lab dog» to «lap dog»: Why Dogs Released from Research Make Great Companions) and Kathleen (Katie) Conlee, (Advocating for Dogs in Laboratories).
>
> Jamie DeRita Memorial Animal Protection Symposium (YouTube)
>
> (Note: We apologize for the technical difficulties during Stacy M. Lopresti-Goodman’s presentation.)
>
>
>
>
> Next Generation Humane Science Award: DEADLINE AUGUST 1, 2020
> DEADLINE EXTENDED to August 1st, 2020
>
> The Next Generation Humane Science Award is available annually to young scientists to acknowledge and encouraging researchers who focus on replacing the use of animals in experiments. The 2020 award will be a prize of up to $5,000 to recognize the work of one young scientist; this may be shared among two or more young scientists. Applications are due no later than August 1st, 2020. Please email completed applications and required information to caat@jhu.edu.
>
> Qualification Criteria
>
> The work must be focused on the replacement of animals used in experimentation. Excellence of research outcome as demonstrated by publications and presentations at scientific meetings. The review committee will also take into account:
>
> The significance of the potential to replace animal experiments in the future.
> Providing an inspiration to others (fellow students, members of the research group) and outreach to wider audiences.
> The potential for the replacement methodologies to be used in a regulatory context.
> 2020 Eligibility Criteria
>
> The candidate must be a citizen or permanent resident of the United States working at a US-based institution.
> The candidate should not have received a PhD or similar degree earlier than 2012.
> Current and former employees (or their family members) of the Center of Alternatives to Animal Testing at Johns Hopkins University cannot apply.
> Application procedure and documentation
>
> Applications are due no later than August 1st, 2020. Please email completed applications and required information to caat@jhu.edu.
>
> Full Application here (PDF)
>
>
>
> CAAT Faculty Receive Excellent Ratings
> The Johns Hopkins Bloomberg School of Public Health has a long tradition and a firm commitment to providing its students with instruction of the highest quality. Each term, the School recognizes faculty who have contributed significantly to the intellectual life of the School through their excellence in teaching.
>
> We would like to express our deepest appreciation and congratulations to two CAAT faculty members who received “excellent” course rankings from students during the fourth term in the 2019-2020 academic year: Kathrin Herrmann, director of CAAT’s Beyond Classical Refinement program, and Alexandra Maertens, program coordinator for our Green Toxicology and Big Data and AI programs.
>
>
> LIVe2021: Lung In Vitro Event for Innovative & Predictive Models
> June 14-15, 2021
> Nice, France
>
> The meeting will focus on predictive in vitro lung models designed for basic research, efficacy, and toxicity testing. It aims to present the state-of-the-art of in vitro lung models and to map out the route for its future development and use.
>
> Registration
> Abstract Submission (Deadline: April 1st, 2021)
> More Hands-On Training and Events at Altertox Academy
>
>
>
> Best wishes from all of us,
> The CAAT Team
>
>
> Upcoming Events
>
>
> Webinars: 3Rs in COVID-19 Research
> (Thomas Hartung is a speaker)
> August 25-26, 2020
> Online
>
> EuroScience Open Forum
> (Thomas Hartung is a speaker)
> September 2-6, 2020
> Online
>
> OpenTox Virtual Conference
> September 21-25
>
> Advances in Cell & Tissue Culture
> September 30-October 1, 2020
> Online
>
> Altertox Skin Sensitization
> October 1-2, 2020
> Hamburg, Germany
>
> ASCCT Annual Meeting
> October 19, 2020
> Online
>
> Altertox Assessing Endocrine Disruptor Compounds with In Vitro Methods
> October 22-23, 2020
> Helsinki, Finland
>
> Altertox Novel In Vitro Methods and AOP Approaches in Genetic Toxicology
> November 5-6, 2020
> Leiden, The Netherlands
>
> 15th Anniversary EPAA Annual Conference
> November 10, 2020
> Brussels
>
> Altertox Hands-on training In Vitro Lung Models
> November 12-13, 2020
> Geneva, Switzerland
>
> TestSmart DNT5: Developmental Neurotoxicity
> November 15-18, 2020
> Konstanz, Germany
>
> Altertox Multi-Organs-Chip (TissUse)
> April 21-23, 2021
> Berlin, Germany
>
> Altertox PBPK Modeling and Quantitative In Vitro-In Vivo Extrapolations
> April 29-30, 2021
> Wageningen, The Netherlands
>
> SAVE THE DATE
> Pan-American Conference for Alternative Methods
> May 12-14, 2021
> Ontario, Canada
>
> LIVe2021 Lung In Vitro Event
> June 14-15, 2021
> Nice, France
>
> 11th World Congress on Alternatives and Animal Use in the Life Sciences
> August 22-26, 2021
> Maastricht, The Netherlands
>
> Free Live WC11 Webinars on 3Rs in COVID-19 Research
> August 25-26, 2020
> Online
>
> EuroScience Open Forum 2020
> September 2-6, 2020
> Trieste, Italy/Online
>
> EPAA 15th Anniversary Annual Conference
> November 10, 2020
> Altertox training on Skin SensitiZation at WC11 (Organised on behalf of EPAA)
> August 22, 2021
> Maastricht, The Netherlands
>
> 21st International Congress of the European Society of Toxicology In Vitro (ESTIV2020)
> November 21-25, 2022
> Barcelona
>
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>
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