REDUCTION AND REFINEMENT IN EXPERIMENTAL DESIGN AND METHODOLOGY. RESEARCH AND DEVELOPMENT OF DRUGS
This course provides the practical and theoretical knowledge and skills regarding experimental design and methodology required by designated veterinarians and other onsite personnel responsible for the welfare and care of laboratory animals in the conduct of experimental procedures.
This course covers the most important aspects in relation to the reduction in the number of animals used in research, experimental design, literature searches and presentation of results. It also deals with refinement through the study of the main non-invasive and minimally invasive techniques and refinement in surgical techniques. The module also provides an overview of the strategy and processes required in research and drug development.
The content of this course also complies with the training requirements set out in European Directive EU63/2010 developed by the European Commission in respect of the following modules: 10. Design of procedures and projects (level 1), 11. Design of procedures and projects (level 2), 22. Principles of surgery and 51. Information provision and retrieval. For details, see: http://ec.europa.eu/environment/chemicals/lab_animals/pdf/Endorsed_E-T.pdf